South Western Sydney Clinical School

Powter B; Jeffreys SA; Sareen H; Cooper A; Brungs D; Po J; Roberts T; Koh ES; Scott KF; Sajinovic M; Vessey JY; de Souza P; Becker TM, 2021, 'Human TERT promoter mutations as a prognostic biomarker in glioma', Journal of Cancer Research and Clinical Oncology, vol. 147, pp. 1007 - 1017, http://dx.doi.org/10.1007/s00432-021-03536-3

Ding PN; Roberts TL; Chua W; Becker TM; Caixeiro N; de Souza P; Gao B; Lee CK; Itchins M; Westman H; Clarke S; Blinman P; Kao S; John T; Leal JL; Bray VJ, 2021, 'Plasma pre-treatment T790M relative allelic frequency in patients with advanced EGFR-mutated non-small cell lung cancer predicts treatment response to subsequent-line osimertinib', Translational Lung Cancer Research, vol. 10, pp. 1623 - 1634, http://dx.doi.org/10.21037/tlcr-20-1125

Adam T; Becker TM; Chua W; Bray V; Roberts TL, 2021, 'The multiple potential biomarkers for predicting immunotherapy response-finding the needle in the haystack', Cancers, vol. 13, pp. 1 - 20, http://dx.doi.org/10.3390/cancers13020277

Pang TCY; Po JW; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2021, 'Circulating tumour cells in pancreatic cancer: A systematic review and meta-analysis of clinicopathological implications', Pancreatology, vol. 21, pp. 103 - 114, http://dx.doi.org/10.1016/j.pan.2020.11.022

Po JW; Ma Y; Balakrishnar B; Brungs D; Azimi F; Cooper A; Saricilar E; Murthy V; de Souza P; Becker TM, 2021, 'PD-L1 Detection on Circulating Melanoma Cells', Methods Mol Biol, vol. 2265, pp. 223 - 233, http://dx.doi.org/10.1007/978-1-0716-1205-7_17

Po JW; Ma Y; Luk AWS; Lynch D; Balakrishnar B; Brungs D; Azimi F; Cooper A; Saricilar E; Murthy V; de Souza P; Becker TM, 2021, 'Single-Cell Analysis of BRAF^V600E and NRAS^Q61R Mutation Status in Melanoma Cell Lines as Method Generation for Circulating Melanoma Cells', Methods Mol Biol, vol. 2265, pp. 277 - 286, http://dx.doi.org/10.1007/978-1-0716-1205-7_21

Brungs D; Minaei E; Piper AK; Perry J; Splitt A; Carolan M; Ryan S; Wu XJ; Corde S; Tehei M; Aghmesheh M; Vine KL; Becker TM; Ranson M, 2020, 'Establishment of novel long-term cultures from EpCAM positive and negative circulating tumour cells from patients with metastatic gastroesophageal cancer', Scientific Reports, vol. 10, http://dx.doi.org/10.1038/s41598-019-57164-6

Jeffreys SA; Powter B; Balakrishnar B; Mok K; Soon P; Franken A; Neubauer H; de Souza P; Becker TM, 2020, 'Endocrine Resistance in Breast Cancer: The Role of Estrogen Receptor Stability', Cells, vol. 9, http://dx.doi.org/10.3390/cells9092077

Pang TCY; Xu Z; Mekapogu AR; Pothula S; Becker TM; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2020, 'An orthotopic resectional mouse model of pancreatic cancer', Journal of Visualized Experiments, vol. 2020, pp. 1 - 13, http://dx.doi.org/10.3791/61726

Sareen H; Garrett C; Lynch D; Powter B; Brungs D; Cooper A; Po J; Koh ES; Vessey JY; McKechnie S; Bazina R; Sheridan M; van Gelder J; Darwish B; Jaeger M; Roberts TL; De Souza P; Becker TM, 2020, 'The role of liquid biopsies in detecting molecular tumor biomarkers in brain cancer patients', Cancers, vol. 12, pp. 1 - 16, http://dx.doi.org/10.3390/cancers12071831

Lynch D; Powter B; Po JW; Cooper A; Garrett C; Koh ES; Sheridan M; van Gelder J; Darwish B; Mckechnie S; Bazina R; Jaeger M; Roberts TL; de Souza P; Becker TM, 2020, 'Isolation of circulating tumor cells from glioblastoma patients by direct immunomagnetic targeting', Applied Sciences (Switzerland), vol. 10, pp. 3338 - 3338, http://dx.doi.org/10.3390/app10093338

Khan T; Scott KF; Becker TM; Lock J; Nimir M; Ma Y; De Souza P, 2020, 'The Prospect of Identifying Resistance Mechanisms for Castrate-Resistant Prostate Cancer Using Circulating Tumor Cells: Is Epithelial-to-Mesenchymal Transition a Key Player?', Prostate Cancer, vol. 2020, pp. 7938280, http://dx.doi.org/10.1155/2020/7938280

Ding PN; Becker T; Bray V; Chua W; Ma Y; Xu B; Lynch D; de Souza P; Roberts T, 2019, 'Plasma next generation sequencing and droplet digital PCR-based detection of epidermal growth factor receptor (EGFR) mutations in patients with advanced lung cancer treated with subsequent-line osimertinib', Thoracic Cancer, vol. 10, pp. 1879 - 1884, http://dx.doi.org/10.1111/1759-7714.13154

Brungs D; Lochhead A; Iyer A; Illemann M; Colligan P; Hirst NG; Splitt A; Liauw W; Vine KL; Pathmanandavel S; Carolan M; Becker TM; Aghmesheh M; Ranson M, 2019, 'Expression of cancer stem cell markers is prognostic in metastatic gastroesophageal adenocarcinoma', Pathology, vol. 51, pp. 474 - 480, http://dx.doi.org/10.1016/j.pathol.2019.03.009

Ding PN; Becker TM; Bray VJ; Chua W; Ma YF; Lynch D; Po J; Luk AWS; Caixeiro N; de Souza P; Roberts TL, 2019, 'The predictive and prognostic significance of liquid biopsy in advanced epidermal growth factor receptor-mutated non-small cell lung cancer: A prospective study', Lung Cancer, vol. 134, pp. 187 - 193, http://dx.doi.org/10.1016/j.lungcan.2019.06.021

Nimir M; Ma Y; Jeffreys SA; Opperman T; Young F; Khan T; Ding P; Chua W; Balakrishnar B; Cooper A; De Souza P; Becker TM, 2019, 'Detection of AR-V7 in Liquid Biopsies of Castrate Resistant Prostate Cancer Patients: A Comparison of AR-V7 Analysis in Circulating Tumor Cells, Circulating Tumor RNA and Exosomes', CELLS, vol. 8, http://dx.doi.org/10.3390/cells8070688

Po JW; Ma Y; Balakrishna B; Brungs D; Azimi F; De Souza P; Becker TM, 2019, 'Immunomagnetic isolation of circulating melanoma cells and detection of PD-L1 status', PLoS ONE, vol. 14, pp. e0211866, http://dx.doi.org/10.1371/journal.pone.0211866

Singh P; de Souza P; Scott KF; Hall BM; Verma ND; Becker TM; Toh JWT; Sajinovic M; Spring KJ, 2019, 'Biomarkers in immune checkpoint inhibition therapy for cancer patients: what is the role of lymphocyte subsets and PD1/PD-L1?', Translational Medicine Communications, vol. 4, http://dx.doi.org/10.1186/s41231-019-0032-9

Ding PN; Ma YF; Roberts TJ; Chua W; Bray VJ; Lynch D; Burke D; Souza PD; Becker TM, 2018, 'Droplet Digital PCR Based Detection of EGFR Mutations in Advanced Lung Cancer Patient Liquid Biopsies: A Comparison of Circulating Tumour DNA Extraction Kits', Journal of Molecular Biomarkers & Diagnosis, vol. 09, http://dx.doi.org/10.4172/2155-9929.1000397

Po JW; Roohullah A; Lynch D; DeFazio A; Harrison M; Harnett PR; Kennedy C; de Souza P; Becker TM, 2018, 'Improved ovarian cancer EMT-CTC isolation by immunomagnetic targeting of epithelial EpCAM and mesenchymal N-cadherin', Journal of Circulating Biomarkers, vol. 7, http://dx.doi.org/10.1177/1849454418782617

Brungs D; Lynch D; Luk AWS; Minaei E; Ranson M; Aghmesheh M; Vine KL; Carolan M; Jaber M; De Souza P; Becker TM, 2018, 'Cryopreservation for delayed circulating tumor cell isolation is a valid strategy for prognostic association of circulating tumor cells in gastroesophageal cancer', World Journal of Gastroenterology, vol. 24, pp. 810 - 818, http://dx.doi.org/10.3748/wjg.v24.i7.810

Pang T; Xu Z; Pothula S; Yang MH; Becker T; Goldstein D; Heeschen C; Pirola R; Wilson J; Apte MV, 2018, '517 - World-First Identification of Circulating Pancreatic Stellate Cells in Metastatic Pancreatic Cancer', Gastroenterology, vol. 154, pp. S - 114, http://dx.doi.org/10.1016/s0016-5085(18)30816-3

Ding PN; Roberts TL; Chua W; Becker TM; Descallar J; Yip PY; Bray V, 2017, 'Clinical outcomes in patients with advanced epidermal growth factor receptor-mutated non-small-cell lung cancer in South Western Sydney Local Health District', Internal Medicine Journal, vol. 47, pp. 1405 - 1411, http://dx.doi.org/10.1111/imj.13555

Pang TCY; Xu Z; Pothula S; Becker T; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2017, 'Circulating pancreatic stellate (stromal) cells in pancreatic cancer-a fertile area for novel research', Carcinogenesis, vol. 38, pp. 588 - 591, http://dx.doi.org/10.1093/carcin/bgx030

Luk AWS; Ma Y; Ding PN; Young FP; Chua W; Balakrishnar B; Dransfield DT; De Souza P; Becker TM, 2017, 'CTC-mRNA (AR-V7) analysis from blood samples—impact of blood collection tube and storage time', International Journal of Molecular Sciences, vol. 18, http://dx.doi.org/10.3390/ijms18051047

Brungs D; Chen J; Aghmesheh M; Vine KL; Becker TM; Carolan MG; Ranson M, 2017, 'The urokinase plasminogen activation system in gastroesophageal cancer: A systematic review and meta-analysis', Oncotarget, vol. 8, pp. 23099 - 23109, http://dx.doi.org/10.18632/oncotarget.15485

Ma Y; Luk A; Young FP; Lynch D; Chua W; Balakrishnar B; de Souza P; Becker TM, 2016, 'Droplet digital PCR based androgen receptor variant 7 (AR-V7) detection from prostate cancer patient blood biopsies', International Journal of Molecular Sciences, vol. 17, http://dx.doi.org/10.3390/ijms17081264

Brungs D; Aghmesheh M; Vine KL; Becker TM; Carolan MG; Ranson M, 2016, 'Gastric cancer stem cells: evidence, potential markers, and clinical implications', Journal of Gastroenterology, vol. 51, pp. 313 - 326, http://dx.doi.org/10.1007/s00535-015-1125-5

Tognela A; Spring KJ; Becker T; Caixeiro NJ; Bray VJ; Yip PY; Chua W; Lim SH; de Souza P, 2015, 'Predictive and prognostic value of circulating tumor cell detection in lung cancer: A clinician's perspective', Critical Reviews in Oncology/Hematology, vol. 93, pp. 90 - 102, http://dx.doi.org/10.1016/j.critrevonc.2014.10.001

Lim SHS; Becker TM; Chua W; Ng WL; De Souza P; Spring KJ, 2014, 'Circulating tumour cells and the epithelial mesenchymal transition in colorectal cancer', Journal of Clinical Pathology, vol. 67, pp. 848 - 853, http://dx.doi.org/10.1136/jclinpath-2014-202499

Becker TM; Caixeiro NJ; Lim SH; Tognela A; Kienzle N; Scott KF; Spring KJ; De Souza P, 2014, 'New frontiers in circulating tumor cell analysis: A reference guide for biomolecular profiling toward translational clinical use', International Journal of Cancer, vol. 134, pp. 2523 - 2533, http://dx.doi.org/10.1002/ijc.28516

Caixeiro NJ; Kienzle N; Lim SH; Spring KJ; Tognela A; Scott KF; de Souza P; Becker TM, 2014, 'Circulating tumour cells-a bona fide cause of metastatic cancer', Cancer and Metastasis Reviews, http://dx.doi.org/10.1007/s10555-014-9502-8

Lim SH; Becker TM; Chua W; Caixeiro NJ; Ng WL; Kienzle N; Tognela A; Lumba S; Rasko JEJ; De Souza P; Spring KJ, 2014, 'Circulating tumour cells and circulating free nucleic acid as prognostic and predictive biomarkers in colorectal cancer', Cancer Letters, vol. 346, pp. 24 - 33, http://dx.doi.org/10.1016/j.canlet.2013.12.019

Rizos H; Menzies AM; Pupo GM; Carlino MS; Fung C; Hyman J; Haydu LE; Mijatov B; Becker TM; Boyd SC; Howle J; Saw R; Thompson JF; Kefford RF; Scolyer RA; Long GV, 2014, 'BRAF Inhibitor Resistance Mechanisms in Metastatic Melanoma: Spectrum and Clinical Impact', CLINICAL CANCER RESEARCH, vol. 20, pp. 1965 - 1977, http://dx.doi.org/10.1158/1078-0432.CCR-13-3122

Becker TM; Boyd SC; Mijatov B; Gowrishankar K; Snoyman S; Pupo GM; Scolyer RA; Mann GJ; Kefford RF; Zhang XD; Rizos H, 2014, 'Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor', ONCOGENE, vol. 33, pp. 1158 - 1166, http://dx.doi.org/10.1038/onc.2013.45

Todd JR; Scurr LL; Becker TM; Kefford RF; Rizos H, 2014, 'The MAPK pathway functions as a redundant survival signal that reinforces the PI3K cascade in c-Kit mutant melanoma', ONCOGENE, vol. 33, pp. 236 - 245, http://dx.doi.org/10.1038/onc.2012.562

Caixeiro NJ; Kienzle N; Lim SH; Spring KJ; Tognela A; Scott KF; De Souza P; Becker TM, 2014, 'Circulating tumour cells - A bona fide cause of metastatic cancer', Cancer and Metastasis Reviews, vol. 33, pp. 747 - 756, http://dx.doi.org/10.1007/s10555-014-9502-8

Carlino MS; Gowrishankar K; Saunders CAB; Pupo GM; Snoyman S; Zhang XD; Saw R; Becker TM; Kefford RF; Long GV; Rizos H, 2013, 'Antiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition following Acquired Resistance to BRAF and/or MEK Inhibition in Melanoma', MOLECULAR CANCER THERAPEUTICS, vol. 12, pp. 1332 - 1342, http://dx.doi.org/10.1158/1535-7163.MCT-13-0011

Todd JR; Becker TM; Kefford RF; Rizos H, 2013, 'Secondary c-Kit mutations confer acquired resistance to RTK inhibitors in c-Kit mutant melanoma cells', PIGMENT CELL & MELANOMA RESEARCH, vol. 26, http://dx.doi.org/10.1111/pcmr.12107

Haferkamp S; Borst A; Adam C; Becker TM; Motschenbacher S; Windhoevel S; Hufnagel AL; Houben R; Meierjohann S, 2013, 'Vemurafenib Induces Senescence Features in Melanoma Cells', JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 133, pp. 1601 - 1609, http://dx.doi.org/10.1038/jid.2013.6

Boyd SC; Mijatov B; Pupo GM; Tran SL; Gowrishankar K; Shaw HM; Goding CR; Scolyer RA; Mann GJ; Kefford RF; Rizos H; Becker TM, 2013, 'Oncogenic B-RAFV(600E) Signaling Induces the T-Box3 Transcriptional Repressor to Repress E-Cadherin and Enhance Melanoma Cell Invasion', JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 133, pp. 1269 - 1277, http://dx.doi.org/10.1038/jid.2012.421

Tran SL; Haferkamp S; Scurr LL; Gowrishankar K; Becker TM; Desilva C; Thompson JF; Scolyer RA; Kefford RF; Rizos H, 2012, 'Absence of Distinguishing Senescence Traits in Human Melanocytic Nevi', JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 132, pp. 2226 - 2234, http://dx.doi.org/10.1038/jid.2012.126

Gowrishankar K; Snoyman S; Pupo GM; Becker TM; Kefford RF; Rizos H, 2012, 'Acquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK Inhibition', JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 132, pp. 1850 - 1859, http://dx.doi.org/10.1038/jid.2012.63

Becker TM, 2012, 'Chromatin Remodeling in Carcinoma Cells', Reviews in Cell Biology and Molecular Medicine, http://dx.doi.org/10.1002/3527600906.mcb.201100031

Scurr LL; McKenzie HA; Becker TM; Irvine M; Lai K; Mann GJ; Scolyer RA; Kefford RF; Rizos H, 2011, 'Selective Loss of Wild-Type p16(INK4a) Expression in Human Nevi', JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 131, pp. 2329 - 2332, http://dx.doi.org/10.1038/jid.2011.197

Jiang CC; Lai F; Tay KH; Croft A; Rizos H; Becker TM; Yang F; Liu H; Thorne RF; Hersey P; Zhang XD, 2010, 'Apoptosis of human melanoma cells induced by inhibition of B-RAF(V600E) involves preferential splicing of bim(S)', CELL DEATH & DISEASE, vol. 1, http://dx.doi.org/10.1038/cddis.2010.48

Becker TM; Philipsz S; Scurr LL; Fung C; Haferkamp S; Kefford RF; Rizos H, 2010, 'Oncogenic B-RAF(V600E) Promotes Anchorage-Independent Survival of Human Melanocytes', JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 130, pp. 2144 - 2147, http://dx.doi.org/10.1038/jid.2010.117

McKenzie HA; Fung C; Becker TM; Irvine M; Mann GJ; Kefford RF; Rizos H, 2010, 'Predicting Functional Significance of Cancer-Associated p16(INK4a) Mutations in CDKN2A', HUMAN MUTATION, vol. 31, pp. 692 - 701, http://dx.doi.org/10.1002/humu.21245

Scurr LL; Pupo GM; Becker TM; Lai K; Schrama D; Haferkamp S; Irvine M; Scolyer RA; Mann GJ; Becker JC; Kefford RF; Rizos H, 2010, 'IGFBP7 Is Not Required for B-RAF-Induced Melanocyte Senescence', CELL, vol. 141, pp. 717 - 727, http://dx.doi.org/10.1016/j.cell.2010.04.021

Irvine M; Philipsz S; Frausto M; Mijatov B; Gallagher SJ; Fung C; Becker TM; Kefford RF; Rizos H, 2010, 'Amino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondria', CELL CYCLE, vol. 9, pp. 829 - 839, http://dx.doi.org/10.4161/cc.9.4.10785

Haferkamp S; Scurr LL; Becker TM; Frausto M; Kefford RF; Rizos H, 2009, 'Oncogene-Induced Senescence Does Not Require the p16(INK4a) or p14ARF Melanoma Tumor Suppressors', JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 129, pp. 1983 - 1991, http://dx.doi.org/10.1038/jid.2009.5

Haferkamp S; Tran SL; Becker TM; Scurr LL; Kefford RF; Rizos H, 2009, 'The relative contributions of the p53 and pRb pathways in oncogene induced melanocyte senescence', AGING-US, vol. 1, pp. 542 - 556, http://dx.doi.org/10.18632/aging.100051

McKenzie H; Becker TM; Scurr LL; Kefford RF; Rizos H, 2009, 'Wild type and melanoma-associated mutant p16(INK4a) proteins do not oligomerize in vivo', PIGMENT CELL & MELANOMA RESEARCH, vol. 22, pp. 131 - 133, http://dx.doi.org/10.1111/j.1755-148X.2008.00530.x

Becker TM; Haferkamp S; Dijkstra MK; Scurr LL; Frausto M; Diefenbach E; Scolyer RA; Reisman DN; Mann GJ; Kefford RF; Rizos H, 2009, 'The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16(INK4a)', MOLECULAR CANCER, vol. 8, http://dx.doi.org/10.1186/1476-4598-8-4

Haferkamp S; Becker TM; Scurr LL; Kefford RF; Rizos H, 2008, 'p16(INK4a)-induced senescence is disabled by melanoma-associated mutations', AGING CELL, vol. 7, pp. 733 - 745, http://dx.doi.org/10.1111/j.1474-9726.2008.00422.x

Rizos H; McKenzie HA; Ayub AL; Woodruff S; Becker TM; Scurr LL; Stahl J; Kefford RF, 2006, 'Physical and functional interaction of the p14(ARF) tumor suppressor with ribosomes', JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 281, pp. 38080 - 38088, http://dx.doi.org/10.1074/jbc.M609405200

Becker TM; Ayub AL; Kefford RF; Mann GJ; Rizos H, 2005, 'The melanoma-associated 24 base pair duplication in p16INK4a is functionally impaired', INTERNATIONAL JOURNAL OF CANCER, vol. 117, pp. 569 - 573, http://dx.doi.org/10.1002/ijc.21265

Becker TM; Rizos H; de la Pena A; Leclercq IA; Woodruff S; Kefford RF; Mann GJ, 2005, 'Impaired inhibition of NF-kappa B activity by melanoma-associated p16INK4a mutations', BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 332, pp. 873 - 879, http://dx.doi.org/10.1016/j.bbrc.2005.05.032

Rizos H; Diefenbach E; Badhwar P; Woodruff S; Becker TM; Rooney RJ; Kefford RF, 2003, 'Association of p14(ARF) with the p120(E4F) transcriptional repressor enhances cell cycle inhibition', JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 278, pp. 4981 - 4989, http://dx.doi.org/10.1074/jbc.M210978200

Fung DCY; Holland EA; Becker TM; Hayward NK; Bressac-de Paillerets B; Mann GJ, 2003, 'eMelanoBase: an online locus-specific variant database for familial melanoma', Human Mutation, vol. 21, pp. 2 - 7, http://dx.doi.org/10.1002/humu.10149

Becker TM; Rizos H; Kefford RF; Mann GJ, 2001, 'Functional impairment of melanoma-associated p16(INK4a) mutants in melanoma cells despite retention of cyclin-dependent kinase 4 binding', CLINICAL CANCER RESEARCH, vol. 7, pp. 3282 - 3288, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000171574600046&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1

Rizos H; Becker TM; Holland EA; Kefford RF; Mann GJ, 1997, 'Differential expression of p16(INK4a) and p16 beta transcripts in B-lymphoblastoid cells from members of hereditary melanoma families without CDKN2A exon mutations', ONCOGENE, vol. 15, pp. 515 - 523, http://dx.doi.org/10.1038/sj.onc.1201217

Holland EA; Beaton SC; Becker TM; Grulet OMC; Peters BA; Rizos H; Kefford RF; Mann GJ, 1995, 'Analysis of the p16 gene, CDKN2, in 17 Australian melanoma kindreds', ONCOGENE, vol. 11, pp. 2289 - 2294, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995TK70200012&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1